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Veterinary
Surgery
In OKC Near Edmond 405-751-3920 |
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Hypertrophic Osteodystrophy HOD or metaphyseal osteopathy is a rare idiopathic disorder affecting the metaphyseal physis of mainly long bones in young large and giant-breed dogs. HOD can result from an abnormality in endochondral ossification (OC) or necrosis of capillary loops that invade the osteochondral complex. HOD appears as a destructive physeal bone lesion often described as a “double-physeal” line lesion. Soft tissue mineralization and interstitial pneumonia may be seen in dogs with HOD. A.Usually seen in Great Danes, Chesapeake Bay Retrievers, German Shepherds and other large breed dogs between 2-8 months of age. B.Clinical Signs 1.Acute onset of generalized mild to severe lameness with reluctance to walk. 2.Metaphyseal areas are usually swollen and painful. 3.Severely affected dogs may present with high fever, anorexia and depression. 4.Some cases will die. C.Diagnosis 1.Radiographic findings: metaphyseal sclerosis and a linear metaphyseal radiolucency parallel to the physis. The radiolucency corresponds to a zone of suppurative inflammation and hemorrhage. 2.The physis may be widened and subperiosteal and extraperiosteal bone formation may be present. 3.HOD has been seen in the mandible, ribs, scapula and metacarpals as well. D.Treatment 1.Supportive care in dogs unwilling to walk. 2.NSAIDS’ and/or steroids with antibiotics. E.Prognosis 1.Some dogs recover fully. 2.Some recover but have growth deformities of the long bones. 3.Unfortunately severely affected dogs may die. |
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